Chlorin E6

From the green alga Chlorella Ellipsoidea photosensitizer chlorin E6 is obtained in photodynamic therapy (PDT) and is used in alternative cancer treatment of malignant tumors. The specificity of the photosensitizer chlorin E6 is its high absorptions in the red spectral range as well as the specific incorporation or accumulation of chlorin E6 – achieved in the respective tumor tissue due to its special molecular characteristics.

Compared to previous photosensitizers, which showed terrible side effects, chlorin E6 has no such unpleasant side effects.

Our specialists lay extremely great importance to the precise matching of the wavelength of the red laser with chlorin E6. The wavelength of 665 nm (nanometers) must be exactly what our lasers emit.

The usual laser devices have but 658nm, which has already led to a loss of efficiency by 20%. Besides, the aspect that photodynamic therapyis very gentle on the patient compared to other treatments, the tumor tissue can be specifically treated and attacked.

For this reason, the chlorin E6 is particularly attractive for use in photodynamic therapy for the treatment of malignant tumors.

A study from Korea in 2009 demonstrated in an animal experiment that the photosensitizer chlorin E6 applied in photodynamic therapy (PDT) resulted in the inhibition of tumor growth. Through the use of the red laser cell internal processes were triggered, the apoptosis – led the cancer cell – to the programmed cell death.

Oncology Reports, 2009, 22 (5). 1085-1091. Doi: 10.3892 / or_00000540. Efficient preparation of highly pure chlorin E6 and its photodynamic anti-cancer activity in a rat tumor model. Authors: Yeon-Hee Moon, Seong-Min Kwon, Hyo-Jun Kim, Kwan-Young Jung, Jong-Hwan Park, Soo-A Kim, Yong-Chul Kim, Sang-Gun Ahn Jung-Hoon Yoon. Affiliations: Department of Pathology, School of Dentistry, Chosun University, Gwangju 500-759, Korea